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Screw Vial Cap Options

Screw vials and closures are high-quality glass containers used for sample storage and chromatography applications, offering a convenient screw-thread design for easy sealing without crimping tools. Made from clear or amber borosilicate glass, these vials are compatible with HPLC, GC, and autosampler systems.

Paired with PTFE/silicone septa screw caps, they provide chemical resistance, airtight sealing, and reduced contamination, making them ideal for pharmaceutical, environmental, and research laboratories.

Screw Vials and Closures – FAQs:

Q1. What are Screw Vials?
Screw vials are small laboratory vials with a threaded neck that can be sealed with screw caps and septa. They are commonly used in chromatography (HPLC, GC, LC-MS) for secure, leak-free sample storage and analysis.


Q2. What are the types of Screw Vials?

  • Standard 2 mL Screw Top Vials – widely used in autosamplers.

  • Wide-Opening Screw Vials – easier for sample filling.

  • Amber Glass Screw Vials – protect light-sensitive samples.

  • Clear Glass Screw Vials – for general analytical use.


Q3. What are Screw Closures?
Screw closures are threaded caps with PTFE/silicone septa that seal screw vials securely. They are available in open-top caps (for autosamplers) and closed-top caps (for storage).


Q4. What are Screw Vials and Closures used for?
They are widely used in:

  • High-Performance Liquid Chromatography (HPLC)

  • Gas Chromatography (GC)

  • Pharmaceutical testing

  • Environmental and forensic analysis

  • Food and beverage quality testing


Q5. What sizes are Screw Vials available in?
Common volumes include:

  • 1.5 mL – 2 mL (standard autosampler size)

  • 10 mL, 20 mL (for larger sample volumes and headspace analysis)


Q6. What materials are Screw Vials made of?
They are generally made from Type I borosilicate glass, which is chemically inert and heat-resistant. Amber glass vials protect light-sensitive compounds.


Q7. What are the advantages of Screw Vials over Crimp Vials?

  • Easier to use – no crimping tool required.

  • Reusable caps – cost-effective.

  • Quick sealing and unsealing.

  • Suitable for general chromatography applications.


Q8. Where to buy high-quality Screw Vials and Closures in India?
You can buy HPLC screw vials, GC screw top vials, autosampler screw vials, and closures from trusted manufacturers, suppliers, and exporters in India. For high-quality screw vials and closures, Simson Chemtech is a reliable manufacturer and supplier in India.



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